Arrestin from nucleated red blood cells binds to bovine rhodopsin in a light-dependent manner

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Each rhodopsin molecule binds its own arrestin.

Arrestins (Arrs) are ubiquitous regulators of the most numerous family of signaling proteins, G protein-coupled receptors. Two models of the Arr-receptor interaction have been proposed: the binding of one Arr to an individual receptor or to two receptors in a dimer. To determine the binding stoichiometry in vivo, we used rod photoreceptors where rhodopsin (Rh) and Arr are expressed at comparabl...

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ژورنال

عنوان ژورنال: FEBS Letters

سال: 1990

ISSN: 0014-5793

DOI: 10.1016/0014-5793(90)80540-y